INCI Sarsasapogenin ，SKIN CONDITIONING

Product Details

Name: Sarsasapogenin

CAS Number: 126-19-2

Molecular Formula: C27H44O3

Molecular Weight: 416.6365 g/mol

Plant Source:

Anemarrhena asphodeloides

Used Part: Dried rhizome

Specification: 98% HPLC

Packaging: 1 kg/bag, 25 kg/drum

Quality Standard: Enterprise standard

Appearance: White to off-white fine powder

Solubility: It is insoluble in water but soluble in organic solvents such as methanol, ethanol and DMSO.

Advantages: It is of natural origin, non-animal origin, with high purity and can be customized according to customer needs.  

Efficacy:

1. Anti-inflammatory Effect

Studies have shown that diosgenin can alleviate the inflammatory response by inhibiting the nuclear factor-kappa B (NF-κB) pathway and has demonstrated significant anti-inflammatory effects in animal experiments.

Literature Reference: The study by Nafeeza M. et al. (2015) showed that diosgenin significantly reduced the inflammatory markers in the mouse model.

2. Immune Regulation

Immune Enhancement

Diosgenin has been found to be able to enhance the function of the immune system, promoting the proliferation of lymphocytes and the secretion of immune factors.

Literature Reference: The study by Zhiyong Z. et al. (2018) indicated that it can enhance the phagocytic ability of macrophages.

3. Antitumor Activity

Some studies have pointed out that diosgenin has the effect of inhibiting the growth of certain cancer cells and exerts its effect by inducing apoptosis and inhibiting tumor angiogenesis.

Literature Reference: In the paper published by Khanna S. et al. (2020), diosgenin showed a significant inhibitory effect on breast cancer cells.

4. Hypoglycemic Effect

Diosgenin has demonstrated the potential to lower blood glucose levels in some animal experiments and can improve insulin sensitivity.

Literature Reference: Jiang Y. et al. (2019) reported in their study that diosgenin had a significant impact on the blood glucose levels of diabetic model mice.

5. Neuroprotective Effect

Preliminary studies have shown that diosgenin has the function of protecting nerve cells and helps to improve the symptoms of neurodegenerative diseases.

Literature Reference: Huang G. et al. (2021) mentioned its positive effect in the Alzheimer's disease model.