Retinol & SPF Anti-Aging Moisturizer An effective anti-aging skincare routine starts with sun protection. Using an SPF day cream in the morning (as prescribed with other sunscreen measures) that also contains retinol will help protect your skin from damage while improving fine lines, wrinkles and rough texture for a glowing skin. Your day cream should be formulated with ceramides to replenish the skin's natural barrier and help prevent moisture loss, and a non-comedogenic moisturizer that won't clog pores. CeraVe Skin Renewing Day Cream is a non-comedogenic anti-aging moisturizer with SPF and encapsulated retinol that is gradually released into your skin, reducing fine lines and wrinkles without irritation.